I'm comfortable with the unknown, that's the point of science. There are places out there, billions of places out there that we know nothing about. And the fact that we know nothing about them excites me, and I want to go out and find out about them.
He's uncertain what's going to happen next. But he is certain that that's actually the point. If this is all a story, then that's what the story means. If it isn't a story, then the exact same is true.